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CASE REPORT
Year : 2019  |  Volume : 2  |  Issue : 2  |  Page : 128-130

Three-Dimensional Conformal focal radiotherapy (30 Gy in 5 fractions) – An useful substitute for Stereotactic radiosurgery In Brain oligometastases: A Single-institutional Case Series


Department of Radiation Oncology, Narayana Super-Specialty Hospital, Howrah, West Bengal, India

Correspondence Address:
Dr. Kazi Sazzad Manir
Department of Radiation Oncology, Narayana Super.Specialty Hospital, 120/1, Andul Road, Howrah - 711 103, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/IJNO.IJNO_15_19

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Stereotactic Radiosurgery/Radiotherapy (SRS/SRT) or neurosurgery is the standard of care for brain oligometastases (≤4 in number). SRS/SRT is only applicable for highly selected patients due to stringent size criteria (≤4 cm) and unavailability of this advanced technology in majority radiation centers in India. Hypofractionated focal 3-dimensional conformal radiotherapy (30 Gy in 5 fractions in 5 consecutive days) represents an attractive clinical alternative to SRS/SRT. In our series, we report dosimetric and clinical outcomes of nine patients (single brain metastatic foci, median size 3.4 cm). Radiotherapy was planned using coplanar and noncoplanar beams, conventional 1 cm multileaf collimators, and 3-mm planning target volume margins on a 6 MV linear accelerator. We were able to achieve sharp-dose falloff and excellent clinical outcome in our short follow-up. This protocol seems to be a feasible and well-tolerated alternative to SRS/SRT. We have designed a long-term Phase III prospective study to validate this regimen in larger population (ineligible for SRS/SRT).


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